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Health/Medical
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Title: Could CANNABIS be the Key to Curing Pancreatic Cancer?
Source: Lew Rockwell/Daily Mail/Harvard University
URL Source: https://www.lewrockwell.com/2019/08 ... y-to-curing-pancreatic-cancer/
Published: Aug 21, 2019
Author: Natalie Rahhal Deputy Health Editor
Post Date: 2019-08-22 09:27:14 by Deckard
Keywords: None
Views: 63
Comments: 3

Tumors disappeared in 70% of mice treated with a pot compound, Harvard study reveals

Cannabis could hold a key to fighting pancreatic cancer – one of the deadliest forms – suggests recent Harvard University research.

Scientists there tested the effects of marijuana-derived compounds called flavonoids on pancreatic cancer cells in petri dishes and on animals with the disease.

Pancreatic cancer is one of the hardest-to-treat forms of the disease, killing 93 percent of sufferers within five years.

Flavonoids treatment killed all the tumor cells in 70 percent of mice with pancreatic cancer that the researchers tested for the study, published in the journal Frontiers of Oncology last month.

The treatment also supercharged more traditional radiation therapy, giving the researchers hope that by 2020, the promising treatment could be ready for testing in humans.

Notably, the compound that the Harvard team is studying comes from cannabis, but is neither a cannabinoid, like CBD, nor a psychoactive component of the plant, like THC.

Instead, flavonids are the compounds present in virtually all plants (including fruits and vegetables) that give them their vibrant colors.

There are more than 6,000 variations of flavonoids but the Harvard scientists see great potential in one found in cannabis and used to make a compound dubbed FBL-03G.

Cannabinoids are already used and studied for treating the unpleasant side effects of standard cancer therapies like chemo and radiation.

In more recent years, a slew of studies have explored the plant’s potential for treating cancer itself.

Research has pointed to the possibility that cannabis may block tumor growth in a variety of ways – but it’s been spotty, and how the plant has these effects remains unclear.

‘People have done studies before showing that sometimes cannabis works against cancer, and sometimes it doesn’t,’ co-author of the new Harvard study, Dr Wilfred Ngwa, told DailyMail.com.

He attributes a lot of these discrepancies to the wide variation in the composition of any given cannabis strain or plant and lack of consistency in this sense from study to study.

Read the Whole Article


Poster Comment:

"What is a pancreas, anyhow? I mean, I don't know what the damn thing does for you, besides give you cancer."

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#1. To: Deckard (#0)

Instead, flavonids are the compounds present in virtually all plants

Ah. So the article could be titled, "Could TOMATOES be the Key to Curing Pancreatic Cancer?

misterwhite  posted on  2019-08-22   11:03:56 ET  Reply   Trace   Private Reply  


#2. To: Deckard (#0)

I really doubt it helps cure but it clearly can not hurt!

"Socialism corrupts and Democratic Socialism corrupts Absolutely"!

Justified  posted on  2019-08-22   12:59:41 ET  Reply   Trace   Private Reply  


#3. To: Deckard (#0)

Could CANNABIS be the Key to Curing Pancreatic Cancer?

Last week (8/15) a fictional title had CBD oil having successfully cured liver cancer; this week CANNABIS is being touted as the cure for pancreatic cancer. This stream of nonsense won't end until CANNIBIS/CBD cures brain cancer.

https://libertysflame.com/cgi-bin/readart.cgi?ArtNum=59691

Title: Wilsonville woman in custody battle over daughter with cancer - for successfully treating her cancer with CBD Oil

The Daily Mail article does indicate the potential for the flavanoid FBL-03G, when used with "a type of smart radiation therapy to shoot the compound directly into metastasized tumors in mice with pancreatic cancer," shows promising results in mice. As the article indicates, "flavonids are the compounds present in virtually all plants (including fruits and vegetables) that give them their vibrant colors."

There is no indication that getting stoned on cannibis cures cancer.

- - - - - - - - - - - - - - - - - - - -

Flavonoids treatment killed all the tumor cells in 70 percent of mice with pancreatic cancer that the researchers tested for the study, published in the journal Frontiers of Oncology (sic - Frontiers in Oncology) last month.

https://www.frontiersin.org/about/publishing-fees

Frontiers in Oncology is another of those pay to publish journals. A respected medical journal it ain't.

https://www.frontiersin.org/about/team

The management team sports a number of doctors — each claiming a Ph.d. Ahhh. doctors of philosophy.

The listed author of the article, "Natalie Rahhal, Deputy Health Editor," is the Deputy Health Editor of the Daily Mail in the UK.

The Daily Mail article also contains the following in a sidebar:

WHAT ARE THE BENEFITS AND DANGERS OF CANNABIS?

Cannabis is an illegal Class B drug in the UK, meaning possession could result in a five year prison sentence and those who supply the drug face up to 14 years in jail.

However, the drug is still widely used for recreational purposes and can make users feel relaxed and happy.

But smoking it - the most common way to consume the drug - can also lead to feelings of panic, anxiety or paranoia.

Scientific studies have shown the drug can alleviate depression, anxiety and stress, but heavy use may worsen depression in the long term by reducing the brain's ability to let go of bad memories.

It can also contribute to mental health problems among people who already have them, or increase users' risk of psychosis or schizophrenia, according to research.

Marijuana can be prescribed for medical uses in more than half of US states, where it is used to combat anxiety, aggression and sleeping problems. Researchers are also looking into whether it could help people with autism, eczema or psoriasis.

Cannabis oil containing the psychoactive chemical THC, which is illegal in the UK, is claimed to have cancer-fighting properties, and a host of patients claim to have recovered from the disease by taking the drug.

And the article also states:

Research has pointed to the possibility that cannabis may block tumor growth in a variety of ways - but it's been spotty, and how the plant has these effects remains unclear.

'People have done studies before showing that sometimes cannabis works against cancer, and sometimes it doesn't,' co-author of the new Harvard study, Dr Wilfred Ngwa, told DailyMail.com.

He attributes a lot of these discrepancies to the wide variation in the composition of any given cannabis strain or plant and lack of consistency in this sense from study to study.

'So maybe the plant we're investigating in Boston is very different from what we're investigating in California,' Dr Ngwa says.

Often, studies look at a chunk of cannabis's constituent parts, so to speak, rather than homing in on how individual compounds might work.

Curious to find out the latter, Dr Ngwa and his team first separated out many parts of the cannabis plant and ran preliminary tests to see which parts showed the most 'activity' againsty tumors.

That's how they landed on the flavonoid FBL-03G.

So they put FBL-03G in a petri dish with pancreatic cancer cells - a type of tumor they happened to already have been studying in their lab - and watched it work.

They also used a type of smart radiation therapy to shoot the compound directly into metastasized tumors in mice with pancreatic cancer.

'We were very surprised with the results we got,' admits Dr Ngwa.

'We expected it to to show some inhibition of tumor growth, but we were quite surprised that it [also] inhibited tumor progression in other parts of the body.

'We actually had to run some [additional] measurements to see if this was really true.'

It was.

[...]

But do these promising results mean that cancer patients should be turning to cannabis, its oils and extracts?

'We get a lot of patients who are asking that question,' says Dr Ngwa.

'We need more studies,' to know that, he says.

'People are just using formulations of cannabis oil and you don't really know what are the active components in those.'

He is fairly confident that there are active, anti-cancer components in cannabis, but that 'each cannabis plant produces completely different levels of active components.'

It's possible, too, that the plants various elements work 'sytnergistically,' Dr Ngwa says, and even deriving a single component, as he and his team did is much cheaper than making most drugs.

But for the time being patients 'need some patience,' he says.

nolu chan  posted on  2019-08-22   13:09:57 ET  Reply   Trace   Private Reply  


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