[Home]  [Headlines]  [Latest Articles]  [Latest Comments]  [Post]  [Mail]  [Sign-in]  [Setup]  [Help]  [Register] 

Joe Biden announces “You Ain’t Black Enough” CRACKERS as fundraiser for his campaign

Jo Jorgensen Wins Libertarian Party Presidential Nomination

Pharmaceutical Industry is the Leading Cause of Death in U.S., and the Largest Criminal Group in the World

Cop Arrested for Terrorizing and Sexually Grooming Little Girl He Stalked on Minecraft

Biden: 'If you have a problem figuring out whether you're for me or Trump, then you ain't black'

“Back Of The Line!” Gretchen Whitmer’s Husband Gets Big Surprise When He Tries To Use His Unpopular Wife’s Name To Take Cuts In Front Of Other Customers Waiting To Have Boats Put In Water

The creaTion of funcTionally a separaTe judicial sysTem ... subservienT To The DemocraTs leaves noT much in The way of peaceful due process --- To resolve differences.

Joe Rogan Just Blew Up the Death Star

Undercover cops to enforce Ohio Covid Laws

‘I Am Very Serious About Them Losing Their Life’: Alabama Mayoral Candidate Calls for Public Hanging of Drug Dealers

Cop Tries to Force Man to Lick What He Thinks is Urine, Tasers Him After He Refuses

We’ve Got Way Too Many Trumps

Visa Files Patent Application for Digital Currency

Thanks Celebrities!

Brainwashing and the New Vocabulary: 12 Words and Phrases I Never Want to Hear Again

Illinois Lawmaker Floats Legislation to Give Governor Pritzker the Power to Confiscate Property Including Cars, Trucks, Food, Gas, Animals, Clothing, etc

NRA Shamefully Silent on Innocent Black Man Who Tried to Stop Cops from Murdering His Girlfriend

Cops Accuse Man of Carjacking His Own Car, Viciously Beat Him to Death

Cover Up: Fauci Approved Chloroquine, Hydroxychloroquine 15 Years Ago to Cure Coronaviruses; “Nobody Needed to Die”

UNHINGED Michigan AG Jumps on CNN Outraged after President Trump Did Not Wear Mask at Ford Plant — Says He’s Not Welcome Here — THREATENS CHARGES AGAINST FORD!

Hyperloop study: Pittsburgh to Chicago in 56 minutes for $93 is feasible

Facebook and YouTube are rushing to delete “Plandemic,” a conspiracy-laden video

Reopen... and Reject

AGW Threatens to Throw “Civilian” Off Bridge

Operation Haircut Defense Fund — GoFundMe set up to Help Single Mothers Fined $1,000 each for cutting hair in Michigan under orders of Nazi Gov. Gretchen Whitmer

Thanks to AG Barr and Senator McConnell, Patriot Act Will Soon Be Much Stronger and More Invasive

Big Brother COVID-19 "Contact Tracing" Involves Clintons, Soros

Enough! (Stop Saying "We're All In This Together)

‘The American friends’:

Covid Nazi: Costco turning tyrannical

New Jersey father’s outrage after a homeowner called the POLICE on him for taking his two children to an empty park to play

Another Reason Why This ‘Pandemic’ Is Looking More Like A Social Engineering Experiment

DEVELOPING: Declassified Rice email documenting WH meeting 1/5/2017 obtained @CBSNews

An audio recording of a conversation between Joe Biden and Petro Poroshenko on May 13, 2016 (Joe busted)

The far right depends on peddling snake oil. That's why Trump taking hydroxychloroquine is no surprise

UFOs Invading Military Airspace Multiple Times Per Month, but Public Won't Be Told More

Psychotherapist: Lockdown Zealots Are Behaving Like Cult Members

Cancer from Radiation Widespread Among 9/11 Responders

Alan Dershowitz, an Associate of Jeffrey Epstein, “You Have No Right NOT to be Vaccinated”

The Coronavirus ‘Dark Winter’ PSYOP: Question Everything and Do Not Comply With Any Government Order

America’s Totalitarian Ruling Class and Its Willing Slaves

Another COVID Small Business Casualty: The American Christian Church

The 10 Worst States in The U.S.

W.H.O. Says Coronavirus ‘May Never Go Away’ and the Public Must Accept Lockdown as New Normal

10 Ways a Roadside Police Stop Can Go Wrong

Police hang “closed” sign on gym door. Owner replaces it with the Bill of Rights and opens up shop.

Oregon Gov Pulls Out All the Stops to Destroy Mother Who Reopened Her Salon

Profiles in Tyranny: Barbara Ferrer, Los Angeles County Director of Public Health

Video Surfaces of Joe Scarborough Joking About Having Affair With Intern and Having to Kill Her

Nice Try: Governor Cuomo Says “Nobody Should Be Prosecuted” for Sticking Sick Coronavirus Patients into New York Nursing Homes

Status: Not Logged In; Sign In

See other Health/Medical Articles

Title: FDA fast tracking makes Houston Methodist first hospital to treat COVID-19 with recovered patient’s blood
Source: Houston Chronicle
URL Source: https://www.houstonchronicle.com/ne ... n-Methodist-first-15165329.php
Published: Mar 30, 2020
Author: Todd Ackerman
Post Date: 2020-03-30 12:47:29 by Willie Green
Keywords: None
Views: 58

Houston Methodist Hospital doctors were all ready to go, but even they were a bit surprised late Saturday afternoon when word came down from the Food and Drug Administration.

They could transfuse the blood from a former COVID-19 patient into one severely ill at the moment.

The Methodist team sprang into action, using just-donated blood from a Houston-area individual whose symptoms had gone away weeks ago but whose antibodies to the coronavirus were now at optimal levels. By Saturday night, the blood was coursing through not just one but two COVID-19 patients in intensive care at Methodist.

With that, the Houston hospital became the nation’s first to enlist convalescent serum therapy, a century-old idea, against the virus now spreading throughout the U.S. Methodist transfused the patients less than a week after the FDA announced it would facilitate use of the experimental therapy because of the expanding public health crisis.

“Kudos to the FDA,” said Dr. Eric Salazar, a physician scientist at Methodist’s Research Institute who is leading the research effort. “They responded very rapidly.”

On Sunday, Salazar said it is “too early still” to assess whether the transfused blood is helping the patients. But he said doctors are hopeful.

That Methodist was the first to test the approach came as something of a surprise after New York Gov. Andrew Cuomo suggested last week it would happen there soon. After the FDA announcement, he said patient recruitment for plasma donations would begin in a matter of days, focused initially on the heavily hit New York City suburb of New Rochelle.

In reality, Methodist’s team was pushing the effort just as furiously.

The use of convalescent serum therapy dates back as far as the 1918 Spanish Influenza, when it was enlisted on quite a few patients with encouraging results. The approach also was used for the measles, mumps and polio in the first half of the 20th century before it became less relevant with the advent of vaccines and antiviral drugs.

Though study of the idea that immunity can be transferred from a healthy individual to a sick one using convalescent plasma has met with varied results, a number of researchers think it’s worth reviving given the absence of any proven treatment for COVID-19, the disease caused by the new coronavirus.

“It’s really a tried and true approach that has its limitation but has been shown to work in principle,” said Vineet Menachery , a virologist at the University of Texas Medical Branch in Galveston. “Transfusing antibodies that bind and inhibit the virus from growing in the blood definitely can reduce the viral load in patients.”

UTMB showed convalescent serum therapy worked in experiments with mice infected with SARS, the new virus’ closely related cousin that in 2013 and 2014 spread globally . Doctors in China have used the approach in a small number of COVID-19 patients and suggested in a journal article last week that it’s been beneficial.

Methodist had already submitted an application for a larger trial using the approach before the FDA announcement came down Tuesday that the agency would consider emergency uses. At that point, it began contacting former patients who had volunteered to the donate their blood.

There didn’t figure to be as many strong candidates here as New York, just because the coronavirus began spreading there a few weeks before it started hitting Houston, important because donors aren’t eligible for the research for some time after being infected.

“We are only at the point now that many of our potential donors’ plasma would be mature enough to use,” said Dr. James Musser, chair of Methodist’s department of pathology and genomic medicine. “That’s roughly 3½ to 4 weeks after their initial diagnosis, including two weeks in which they’re symptom free. That’s when their antibodies are at maximal level.”

But one such former patient met the criteria last week. Methodist doctors collected and processed the individual’s blood Saturday, the day they applied to the FDA for emergency use of the therapy. With unusual speed, the agency fast-tracked the approval.

On Sunday, Salazar and Musser expressed their gratitude to the donor. They said they were lucky the FDA acted so quickly.

Musser said they expect to be ready to do more transfusions later this week as more donors’ blood becomes ready. Salazar said that more than two-thirds of Methodist patients — roughly 250 have tested positive for COVID-19 at the system's hospitals — may meet the criteria for donation.

Donors each give a quart of blood plasma in a procedure much like donating whole blood.

This is not the first revival of convalescent serum therapy. In the past two decades, it’s been used for SARS in 2003, swine flu in 2009 and Ebola in 2014.

There’s no guarantee of its effectiveness, say researchers.

There is no playbook for treatment, said Menachery. Its success can depend on blood variability from person to person, and the kinetics of when’s best to give it are unclear, though sooner is better. If it’s given late in the disease, sometimes too much damage has already already done.

A playbook is what the new research aims to produce. Besides emergency uses approved on a case-by-case basis, Musser expects that the FDA will lump all the non-emergency trials being proposed by researchers into one umbrella trial that pools resources and findings.

“It’s really remarkable how everyone’s come together on this in such a grassroots fashion,” said Musser. “It’s all hands on deck.”

Poster Comment:

Gotta be a helluva lot more credible than that fraudulent fish tank cleaner being hyped by Rooty Giuliani's quack doctor...

The FDA can move mighty fast when it's an emergency...

Post Comment   Private Reply   Ignore Thread  

[Home]  [Headlines]  [Latest Articles]  [Latest Comments]  [Post]  [Mail]  [Sign-in]  [Setup]  [Help]  [Register] 

Please report web page problems, questions and comments to webmaster@libertysflame.com